ABSTRACT Objective To describe accidents involving brown spider (genus Loxosceles) bites notified by the Pernambuco Poison Information and Care Center (CIATox-PE), Brazil, from January 2018 to December 2022. Methods This was a case series study of brown spider bites notified by the CIATox-PE. Results The study included 22 cases with median age of 35 years, the majority being female (13); the cases occurred in rural and urban areas (12 versus 10), at night (10); Petrolina was the municipality with the highest number of notifications (6); spider bites occurred mainly in the lower (11) and upper (9) limbs, almost exclusively inside households (21); specific serum therapy was not indicated for 8 cases because the time for its effectiveness had already elapsed. Conclusion Loxoscelism cases occurred more frequently in females, in both rural and urban areas and mainly at home, with delays in seeking medical care.

RESUMEN Objetivo Describir accidentes causados por arañas pardas (género Loxosceles) notificados por el Centro de Información de Asistencia Toxicológica de Pernambuco (CIATox-PE), Brasil, de enero de 2018 a diciembre de 2022. Métodos Reporte de 22 casos notificados de CIATox-PE. Resultados Casos con media de idade de 35 años, predominio femenino (13); los casos ocurrieron en área rural/urbana (12 versus 10), por la noche (10); Petrolina fue el municipio con más notificaciones (6); las picaduras fueron principalmente en los miembros inferiores (11) y superiores (9), casi exclusivamente en el interior de las viviendas (21); en 8 de los casos no se indicó sueroterapia específica por haber superado el tiempo de efecto. Conclusión Los casos de loxoscelismo ocurrieron con mayor frecuencia en el sexo femenino, en áreas rurales y urbanas, y principalmente en el hogar, con demoras en la búsqueda de atención médica.

RESUMO Objetivo Descrever os acidentes por picada de aranhas-marrons (gênero Loxosceles), notificados no Centro de Informação de Assistência Toxicológica de Pernambuco (CIATox-PE), Brasil, no período de 2018 a 2022. Métodos Estudo de série, sobre casos notificados no CIATox-PE. Resultados Foram incluídos 22 casos com mediana de idade de 35 anos e houve predomínio do sexo feminino (13); os casos ocorreram nas zonas rural e urbana (12 versus 10), durante a noite (10), e Petrolina foi o município com mais notificações (6); as picadas ocorreram, principalmente, nos membros inferiores (11) e superiores (9), quase exclusivamente dentro das residências (21); para 8 acidentados, não se prescreveu soroterapia específica por terem ultrapassado o tempo de efetividade. Conclusão Os casos de loxoscelismo ocorreram com maior frequência no sexo feminino, nas zonas rural e urbana indiferentemente, quase todos foram intradomiciliares e houve demora na procura por atendimento médico.

RESUMO Objetivo Descrever os acidentes por picada de aranhas-marrons (gênero Loxosceles), notificados no Centro de Informação de Assistência Toxicológica de Pernambuco (CIATox-PE), Brasil, no período de 2018 a 2022. Métodos Estudo de série, sobre casos notificados no CIATox-PE. Resultados Foram incluídos 22 casos com mediana de idade de 35 anos e houve predomínio do sexo feminino (13); os casos ocorreram nas zonas rural e urbana (12 versus 10), durante a noite (10), e Petrolina foi o município com mais notificações (6); as picadas ocorreram, principalmente, nos membros inferiores (11) e superiores (9), quase exclusivamente dentro das residências (21); para 8 acidentados, não se prescreveu soroterapia específica por terem ultrapassado o tempo de efetividade. Conclusão Os casos de loxoscelismo ocorreram com maior frequência no sexo feminino, nas zonas rural e urbana indiferentemente, quase todos foram intradomiciliares e houve demora na procura por atendimento médico.

RESUMEN Objetivo Describir accidentes causados por arañas pardas (género Loxosceles) notificados por el Centro de Información de Asistencia Toxicológica de Pernambuco (CIATox-PE), Brasil, de enero de 2018 a diciembre de 2022. Métodos Reporte de 22 casos notificados de CIATox-PE. Resultados Casos con media de idade de 35 años, predominio femenino (13); los casos ocurrieron en área rural/urbana (12 versus 10), por la noche (10); Petrolina fue el municipio con más notificaciones (6); las picaduras fueron principalmente en los miembros inferiores (11) y superiores (9), casi exclusivamente en el interior de las viviendas (21); en 8 de los casos no se indicó sueroterapia específica por haber superado el tiempo de efecto. Conclusión Los casos de loxoscelismo ocurrieron con mayor frecuencia en el sexo femenino, en áreas rurales y urbanas, y principalmente en el hogar, con demoras en la búsqueda de atención médica.

ABSTRACT Objective To describe accidents involving brown spider (genus Loxosceles) bites notified by the Pernambuco Poison Information and Care Center (CIATox-PE), Brazil, from January 2018 to December 2022. Methods This was a case series study of brown spider bites notified by the CIATox-PE. Results The study included 22 cases with median age of 35 years, the majority being female (13); the cases occurred in rural and urban areas (12 versus 10), at night (10); Petrolina was the municipality with the highest number of notifications (6); spider bites occurred mainly in the lower (11) and upper (9) limbs, almost exclusively inside households (21); specific serum therapy was not indicated for 8 cases because the time for its effectiveness had already elapsed. Conclusion Loxoscelism cases occurred more frequently in females, in both rural and urban areas and mainly at home, with delays in seeking medical care.

RESUMEN La pérdida ósea marginal periimplantaria (MBL) es un proceso de remodelación no infeccioso que ocurre durante el primer año después de la colocación de un implante dental y todavía en la actualidad, sigue siendo un proceso complejo que sigue suscitando dudas. La asociación entre MBL y enfermedades periimplantarias todavía no está clara del todo, sin embargo, algunos autores así lo han establecido. Por este motivo, el control temprano de la MBL puede ser un factor clave en la prevención de la periimplantitis. Se han descrito factores generales y sistémicos del paciente, factores quirúrgicos asociados a la propia colocación del implante o a los tejidos duros y blandos que lo rodean, pero también a factores prostodónticos y de oclusión. El control de la posición del implante y el volumen de los tejidos, de la estabilidad primaria, de la inflamación postoperatoria y tardía, así como el momento de la carga, el tipo de prótesis o la forma y la altura del pilar, son algunos de los factores identificados como clave actualmente. El objetivo de este trabajo es describir desde un punto de vista reflexivo, la implicación de todos estos factores en el control de la MBL.

ABSTRACT Peri-implant marginal bone loss (MBL) is a non-infectious remodelling process that occurs during the first year after the placement of a dental implant and even today, it remains a complex process that continues to raise questions. The association between MBL and peri-implant diseases is still not entirely clear, however, some authors have established it. For this reason, early control of MBL may be a key factor in the prevention of peri-implantitis. General and systemic factors of the patient have been described, surgical factors associated with the actual placement of the implant or the surrounding hard and soft tissues, but also prosthodontic and occlusion factors. The control of the position of the implant and the volume of the tissues, of the primary stability, of the postoperative and late inflammation, as well as the moment of the load, the type of prosthesis or the shape and height of the abutment, are some of the factors currently identified as key. The objective of this work is to describe, from a reflexive point of view, the implication of all these factors in the control of MBL.

Abstract The formulation of alternative substrates using organic residues from agro-industrial/agricultural activities allows, in addition to reducing production costs, to reduce environmental impacts. Carnauba bagana, a residue from the extraction of wax, has great potential in the formulation of alternative substrates. However, studies using this residue as a raw material in the composition of substrates for the production of plant loofah seedlings have not yet been carried out. Thus, the present research aimed to evaluate the potential of substrates composed of different mixtures of soil and carnauba bagana in the production of plant loofah seedlings. The experiment was carried out in a greenhouse under a completely randomized design, with six treatments (0, 20, 40, 60, 80 and 100% carnauba bagana, plus soil) and four replications. According to the results obtained, it was possible to verify that the carnauba bagana can be used as a constituent of substrate for the production of plant loofah seedlings. Among the combinations tested, the mixture consisting of 50% carnauba bagana + 50% soil showed the greatest potential for use.

Resumo A formulação de substratos alternativos utilizando resíduos orgânicos provenientes de atividades agroindustriais/agropecuárias possibilitam, além da redução de custos de produção, a redução de impactos ambientais. A bagana de carnaúba, um resíduo oriundo da extração da cera, possui grande potencial na formulação de substratos alternativos. Contudo, ainda não foram realizados estudos utilizando esse resíduo como matéria-prima na composição de substratos para a produção de mudas de bucha vegetal. Assim, a presente pesquisa teve como objetivo avaliar o potencial de substratos compostos por diferentes misturas de solo e bagana de carnaúba na produção de mudas de bucha vegetal. O experimento foi conduzido em casa de vegetação sob delineamento inteiramente casualizado, com seis tratamentos (0, 20, 40, 60, 80 e 100% bagana de carnaúba, acrescido de solo) e quatro repetições. De acordo com os resultados obtidos foi possível constatar que a bagana de carnaúba, pode ser empregada como constituinte de substrato para produção de mudas de bucha vegetal. Entre as combinações testadas, a mistura constituída por 50% de bagana de carnaúba + 50% de solo foi a que apresentou maior potencial de utilização.

Resumo Objetivos: realizar uma revisão sistemática de estudos que investigaram a influência do consumo de alimentos ultraprocessados (AUP) na gestação nas medidas antropométricas do recém-nascido até um ano de idade. Métodos: foram pesquisados estudos de coorte e transversais nas bases BVS, Cinahl, Cochrane, Embase, Pubmed, Scopus e Web of Science até março de 2020, tendo como principais descritores: “Pregnant women”, “Ultra-processed foods”, “Birth weight”, “Small for Gestational Age”, “Infant”, “Newborn”. Resultados: dezessete artigos foram considerados elegíveis e avaliaram as associações entre as exposições: padrões alimentares ultraprocessados; refrigerantes, sugar-sweetened beverages ou artificially sweetened beverages; fastfood, junkfood, doces e snacks e os desfe-chos:peso ao nascer e suas classificações; comprimento e perímetro cefálico ao nascimento; adequações do peso ao nascer segundo idade gestacional; e índices peso/idade, compri-mento/idade, índice de massa corporal/idade e peso/comprimento. Foram encontradas: 36 associações nulas entre exposições e desfechos avaliados; 13 diretas (desfechos versus padrões alimentares ultraprocessados, refrigerantes, artificially sweetened beverages, doces e junkfood) e 5 inversas (desfechos versus padrões alimentares ultraprocessados e refrigerantes). Conclusões: a maioria da literatura avaliada não demonstrou influência do consumo de AUP na gestação nas medidas antropométricas do recém-nascido até um ano de vida e apontou um menor número de associações diretas e inversas entre as exposições e os desfechos analisados.

Abstract Objectives: to perform a systematic review of studies that investigated the influence of ultra-processed foods (UPF) consumption during pregnancy on child’s anthropometric parameters up to one year of life. Methods: cohort and cross-sectional studies were researched in BVS, Cinahl, Cochrane, Embase, Pubmed, Scopus and Web of Science databases until March 2020, and the main descriptors were: “Pregnant Women”, “Ultra-processed foods”, “Birth Weight”, “Smallfor Gestational Age”, “Infant”, “Newborn”. Results: seventeen articles were considered eligible and evaluated the associations between the exposures: ultra-processed dietary patterns; soft drinks, sugar-sweetened beverages, artificially sweetened beverages; fast food, junk food, sweets, snacks and the outcomes: birth weight and its classifications; length and head circumference at birth; birth weight adjustments according to gestational age; weight/age, length/age, body mass index/age and weight/length indices. The results showed: 36 non-significant associations between the exposures and the outcomes; 13 direct associations (outcomes versus ultraprocessed dietary patterns, soft drinks, artificially sweetened beverages, sweets, junk food) and 5 inverse associations (outcomes versus ultra-processed dietary patterns, soft drinks). Conclusions: most of the evaluated literature did not demonstrate the influence of UPF consumption during pregnancy on the newborn’s anthropometric measurements up to one year of life and denoted a smaller number of direct and inverse associations between the exposures and the outcomes.

ABSTRACT The objective was to group and characterize Zebu cattle carcasses according to sex. Data from 15,002 carcasses of cattle raised in the semiarid region of the state of Minas Gerais, Brazil, were used. The carcass characteristics analyzed were weight, conformation, subcutaneous fat, number of permanent incisor teeth (PIT), and sex (uncastrated males, castrated males, females (up to six PIT), and cows (eight PIT)). Cluster analysis was applied to establish the relationship between sex and carcass characteristics. Four clusters were identified according to sex, and 60% of the total variance in the data set is explained by the clusters. Uncastrated males appear together in a single group (Cluster 1), which demonstrates homogeneity in their carcass characteristics. The heaviest group was Cluster 1. The castrated males appear in three groups, some of them (33.58%) grouped with the majority of cows (92.85%), which indicates that these carcasses did not achieve the quality required by the industry. Another part of the castrated males (41.84%) presented characteristics required by the industry. The females appear in all clusters. Except for uncastrated males and cows, the effect of sex (castrated males and females) on the carcass characteristics of Zebu cattle from the semiarid region of the Minas Gerais does not assure similar characteristics. Therefore, the improvement of carcass quality, using castration as the central grading criterion, should be reviewed not to overemphasize this item.

RESUMO O conhecimento da prevalência da cisticercose bovina é importante para a implementação de programas de controle. Objetivou-se avaliar a prevalência e a distribuição geográfica de cisticercose bovina no Norte de Minas Gerais. Para isso, avaliou-se 14556 bovinos durante a inspeção federal post mortem provenientes de 27 municípios de cinco microrregiões: Janaúba, Montes Claros, Januária, Pirapora e Bocaiúva. A prevalência de Cysticercus bovis foi de 1,03% e está distribuída geograficamente em todas as microrregiões avaliadas do Norte de Minas Gerais avaliadas. Todos os municípios com número amostral de bovinos abatidos acima de 543 apresentaram animais positivos para cisticercose. As microrregiões de Bocaiúva, Montes Claros, Janaúba, Januária e Pirapora apresentaram prevalência de cisticercose de 2,11%, 1,17%, 1,01%, 0,90% e 0,56%, respectivamente. As microrregiões de Montes Claros e Januária apresentaram maior chance de se encontrar bovinos positivos para cisticercose. Como há casos positivos de cisticercose em todas as microrregiões avaliadas, há risco a saúde dos seres humanos.

ABSTRACT The knowledge of the prevalence of bovine cysticercosis is important for the implementation of control programs. The objective was to evaluate the prevalence and geographical distribution of bovine cysticercosis in Northern Minas Gerais. For that, 14,556 cattle were evaluated during the federal post-mortem inspection in 27 municipalities of five microregions: Janaúba, Montes Claros, Januária, Pirapora and Bocaiúva. The prevalence of Cysticercus bovis was 1.03% with distribution in all microregions evaluated of the northern Minas Gerais. All municipalities with a sampling number of cattle slaughtered above 543 showed positive animals for cysticercosis. The microregions of Bocaiúva, Montes Claros, Janaúba, Januária and Pirapora presented a prevalence of cysticercosis at 2.11%, 1.17%, 1.01%, 0.90% and 0.56%, respectively. The microregions of Montes Claros and Januária presented a greater chance of finding positive cattle for cysticercosis. As there are positive cases of cysticercosis in all microregions evaluated, there is a risk to human health.

ABSTRACT Actinomycosis is an uncommon, endogenous, and chronic infection with varied and nonspecific clinical features such as abdominal, pelvic or cervical masses, ulcerative lesions, abscesses, draining fistula, fibrosis, and constitutional symptoms. The disease ensues when the bacteria disrupt the mucosal barrier, invade, and spread throughout interfascial planes. Currently, the diagnosis of actinomycosis is challenging because of its very low frequency and depending on the clinical presentation it may masquerade malignancies. Therapy consists initially in intravenous penicillin, followed by an oral regimen that may be extended until a year of treatment. A timely diagnosis is crucial to avoid extensive therapeutic attempt as surgery. However, a biopsy or drainage of abscesses and fistula’s tract may be required not only as a diagnostic procedure as part of the therapy. We report the case of a 72-year-old woman with an abdominal mass initially misdiagnosed as a liposarcoma. A second biopsy of a skin lesion of the abdominal wall made the diagnosis of actinomycosis, avoiding a major surgical procedure. The patient was treated with a long-term course of antibiotics with favorable outcome. Liposarcoma was ruled out after the patient’s full recovery with antibiotics and the misdiagnosis was credit to the overconfidence on the immunohistochemical positivity to MDM2.

RESUMO CONTEXTO: A infecção por Helicobacter pylori é o fator de risco mais importante para atrofia gástrica e metaplasia intestinal, ambas consideradas lesões precursoras do câncer gástrico. Portanto, a investigação da ocorrência de infecção por H. pylori, das lesões precursoras e dos fatores associados orienta a adoção de estratégias específicas para o controle deste tipo de câncer. OBJETIVO: Avaliar a prevalência de infecção por H. pylori em pacientes submetidos à endoscopia digestiva alta, bem como a prevalência de metaplasia intestinal, atrofia e inflamação crônica e a associação destas com a infecção por H. pylori. MÉTODOS: Foi realizado um estudo retrospectivo com base em laudos de biópsias endoscópicas gástricas realizadas em laboratório privado afiliado ao Sistema Único de Saúde (SUS). Os pacientes foram avaliados quanto à idade, sexo e tipo de serviço de saúde. As amostras foram avaliadas quanto à presença de H. pylori e também de inflamação crônica, metaplasia intestinal e atrofia glandular. RESULTADOS: Do total de 4.604 pacientes (idade média de 51±16,6), 63,9% eram do sexo feminino e 63,1% provenientes de serviços de saúde privado. A prevalência de infecção por H. pylori foi de 31,7% (n=1.459) e o percentual de infecção foi significativamente maior nos pacientes do serviço público de saúde (42,0%) em relação aos pacientes do serviço privado de saúde (25,6%). Entre os pacientes com H. pylori (+), foi observado maior percentual de metaplasia intestinal (17,7% vs 13,3%) e atrofia glandular (17,6% vs 6,9%) quando comparados aos H. pylori (-) (P<0,01). Dos pacientes H. pylori (+) com pelo menos um tipo de lesão precursora (n=418), 161 (38,5%) apresentaram metaplasia e inflamação crônica, 160 (38,3%) apresentaram atrofia e inflamação crônica e, finalmente, 97 (23,2%) apresentaram metaplasia, atrofia e inflamação crônica simultaneamente. CONCLUSÃO: O presente estudo reforça a associação da infecção por H. pylori com lesões precursoras de câncer gástrico em uma população brasileira, enfatizando a importância de medidas de prevenção de infecção, bem como o tratamento de pacientes infectados, principalmente em regiões com níveis socioeconômicos mais baixos que apresentam maior prevalência de infecção por H. pylori.

ABSTRACT BACKGROUND: Helicobacter pylori infection is the most important risk factor for gastric atrophy and intestinal metaplasia, both considered gastric cancer precursor lesions. Therefore, the investigation of the occurrence of H. pylori infection, precursor lesions and associated factors guides the adoption of specific strategies for the control this type of cancer. OBJECTIVE: To evaluate the prevalence of H. pylori infection in patients undergoing upper digestive endoscopy, as well as the prevalence of intestinal metaplasia, atrophy and chronic inflammation and their association with H. pylori infection. METHODS: A retrospective study was performed based on reports of gastric endoscopic biopsies performed in a private laboratory affiliated to the Brazilian Public Health System (SUS). Patients were evaluated for age, gender and type of health service. The samples were evaluated for the presence of H. pylori, and also of chronic inflammation, intestinal metaplasia and glandular atrophy. RESULTS: Of a total of 4,604 patients (mean age 51±16.6), 63.9% were female and 63.1% coming from private health care service. The prevalence of H. pylori infection was 31.7% (n=1,459), and the percentage of infection was significantly higher in patients from public health service (42.0%) in relation to patients from private health service (25.6%). Among H. pylori (+) patients, a higher percentage of intestinal metaplasia (17.7% vs 13.3%) and glandular atrophy (17.6% vs 6.9%) were observed when compared to those H. pylori (-) (P<0.01). From the patients H. pylori (+) with at least one type of precursor lesion (n=418), 161 (38.5%) had metaplasia and chronic inflammation, 160 (38.3%) had atrophy and chronic inflammation and finally 97 (23.2%) presented metaplasia, atrophy and chronic inflammation simultaneously. CONCLUSION: The present study reinforces the association of H. pylori infection with gastric cancer precursor lesions in a Brazilian population, emphasizing the importance of infection prevention measures, as well as the treatment of infected patients, especially in regions with lower socioeconomic levels that show a higher prevalence of infection by H. pylori.

RESUMO Objetivou-se avaliar os níveis de casca de banana seca ao sol na dieta de vacas F1 Holandês x Zebu sobre o perfil de ácidos graxos do leite e do queijo minas frescal. Os tratamentos foram constituídos de 0, 15, 30, 45 e 60% de substituição da silagem de sorgo pela casca de banana. O delineamento experimental foi em dois quadrados latinos 5 x 5 simultâneos. As amostras de leite e queijo foram analisadas quanto ao perfil de ácidos graxos por cromatografia gasosa. Observou-se efeito quadrático para o somatório de ácidos graxos poli-insaturados do leite, com valor máximo no nível de 23,54% de substituição. Houve efeito linear decrescente para os ácidos graxos C15:0 iso e C16:0 iso. Os ácidos graxos heneicosanoico, linoleico, linoleico conjugado e araquidônico apresentaram efeito quadrático. Não houve efeito das dietas sobre os ácidos graxos no queijo. A substituição de até 60% da silagem de sorgo por casca de banana na dieta de vacas em lactação pode ser alternativa para produção e processamento do leite, quando se considera a melhora no valor nutricional da fração lipídica do leite e o aumento dos teores de ácido linoleico conjugado.

ABSTRACT This study aimed to evaluate the inclusion levels of dry banana peel in the sun in the diet of F1 Holstein x Zebu cows on the profile of fatty acids of milk and Minas fresh cheese. The diets were composed of 0, 15, 30, 45, and 60% replacement of sorghum silage by banana peel. The experimental design was Latin squares, simultaneous, 5 x 5. Samples of milk and cheese were analyzed for fatty acid composition by gas chromatography. Quadratic effect for the sum of milk polyunsaturated fatty acids, with the maximum level of 23,54% replacement. There was a decreasing linear effect for C15:0 iso fatty acids and C16: 0 iso. The heneicosanoic fatty acids, linoleic, conjugated linoleic and arachidonic presented quadratic effect. There was no effect of diets on fatty acids in cheese. Replacement of up to 60% of the sorghum silage of a banana peel in the diet of cows can be an alternative to milk production and processing when considering the improvement in the nutritional value of the milk lipid fraction and increase of the levels of conjugated linoleic acid.

Asphaltenes are a heavy fraction of petroleum with the ability for self-association, a phenomenon that can occur spontaneously in the reservoirs or in any of the various stages of production and processing, depending on variations in pressure, temperature, composition and shearing, among others. In this work, it was evaluated the precipitation of asphaltenes in two oils (P01 and P02) in different conditions of temperature and pressure and in the absence or presence of CO2. Under high pressure and temperature conditions, the precipitation of asphaltenes was observed in the presence of CO2 in mixtures with methane, while the addition of propane induced precipitation in the absence of CO2. The results of analyses elemental (CHNO), SEM, FTIR and LDI-MS were consistent with the structure assigned to samples of this nature (oils, maltenes and fractions of asphaltenes insoluble in n-pentane, C5I, and n-heptane, C7I).

ABSTRACT The objective of this study was to evaluate performance and carcass and meat characteristics of lambs fed a solution of cheese whey plus water (100 g kg−1 dry matter) (CW) during feedlot and pre-slaughter lairage. Data were analyzed as a 2 × 2 factorial (place – feedlot and slaughterhouse, food – water or CW). We evaluated the following treatments (feedlot/slaughterhouse): CW/CW, CW/water, water/CW, and control (water/water). The lambs were given a balanced diet for 70 days in the feedlot. Slaughter started 12 h after the animals arrived at the slaughterhouse. Dry matter intake, gain-to-feed ratio, average daily gain, and body weight of lambs fed CW were similar to those of control lambs. The water/CW group consumed less of this solution than the CW/CW group in the slaughterhouse. The CW supplied as a pre-slaughter supplement reduces the drip losses of lamb carcasses provided that the animals also consume it during the feedlot period. The other carcass characteristics (carcass weight, pH, subcutaneous fat thickness, and ribeye area) were similar among treatments. The meat characteristics (color, water holding capacity, cooking losses, and shear force) were similar among treatments. Whey cheese added to water can be used as an ingredient of the diet for lambs and as pre-slaughter supplement, since it does not change performance and improves carcass characteristics.